Efectividad del Doppler de la Arteria Uterina Versus Biomarcadores como Predictores Tempranos de Preeclampsia: Una Revisión Sistemática
Resumen
Introducción: La preeclampsia es una de las principales causas de morbimortalidad materna y perinatal. La disfunción placentaria y el desequilibrio en los factores angiogénicos ocurren antes de que aparezcan los síntomas clínicos, lo que ha llevado a utilizar el Doppler de la arteria uterina y biomarcadores angiogénicos como métodos para una predicción temprana. Objetivo: Analizar la efectividad del Doppler de la arteria uterina frente a biomarcadores angiogénicos, solos o combinados, como predictores tempranos de preeclampsia. Métodos y resultados: Se realizó una revisión sistemática siguiendo PRISMA 2020, incluyendo 13 estudios publicados entre 2020 y 2025. Los modelos combinados (Doppler uterino, PlGF, sFlt-1/PlGF y variables clínicas) mostraron mayor rendimiento diagnóstico, con AUC entre 0,84 y 0,92, superando al uso aislado del Doppler. Conclusión: La integración de biomarcadores angiogénicos y Doppler uterino constituye la estrategia más efectiva para la predicción temprana de preeclampsia
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Derechos de autor 2026 Gabriela Cecilia Medina Pucha , Maria Caridad Cabrera Erazo , Monica Elizabeth Alvarado Guaman
Esta obra está bajo licencia internacional Creative Commons Reconocimiento 4.0.
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